BIOMATERIALS

AIM

This course is designed to provide a general understanding of the multidisciplinary field of biomaterials. The course mainly deals with biomaterials, properties, biomedical applications, biocompatibility and biodegradability, toxicity of the materials as well as interactions at the interface of material and biological systems. Current applications of biomaterials will be evaluated to provide an understanding of material bulk and surface properties, degradation processes, various biological responses to the materials and the clinical context of their use.

CONTENT

This course contains; Introduction and History of Biomaterials,Mechanical and Surface Properties of Biomaterials,Polymeric Biomaterials,Polymeric Biomaterials, Dental Biomaterials and Hydrogels,Degradation of Biomaterials,Metalic Biomaterials,Ceramic Biomaterials,Composite Biomaterials,Macro and Nanoparticles,Processing of Biomaterials,Biomaterials-Protein Interaction,Host Response to Biomaterials,Testing Biomaterials,Production and Life Cycle of Biomaterials and Commercialization Paths.

1. 1

   Define the fundamental principles of biomaterials and their properties,

   Taught by: Discussion Method, Self Study Method, Question - Answer Technique, Computer-Internet Supported Instruction, Lecture Method · Assessed by: Traditional Written Exam, Homework, Quiz

2. 2

   Classify biomaterials according to the structural properties

   Taught by: Discussion Method, Self Study Method, Question - Answer Technique, Computer-Internet Supported Instruction, Lecture Method · Assessed by: Traditional Written Exam, Homework, Quiz

3. 3

   Evaluate the modern analytical techniques for characterization of biomaterials,

   Taught by: Discussion Method, Self Study Method, Question - Answer Technique, Computer-Internet Supported Instruction, Lecture Method · Assessed by: Traditional Written Exam, Homework, Quiz

4. 4

   Evaluates interactions between biomaterials and the body

   Taught by: Discussion Method, Self Study Method, Question - Answer Technique, Computer-Internet Supported Instruction, Lecture Method · Assessed by: Traditional Written Exam, Homework, Quiz

5. 5

   Compares biomaterials according to the application fields

   Taught by: Discussion Method, Self Study Method, Question - Answer Technique, Computer-Internet Supported Instruction, Lecture Method · Assessed by: Traditional Written Exam, Homework, Quiz

6. 6

   Suggests biomaterials for a specific application

   Taught by: Discussion Method, Self Study Method, Question - Answer Technique, Lecture Method · Assessed by: Traditional Written Exam, Homework, Quiz

WEEKLY PLAN

1. WEEK 1

   Introduction and History of Biomaterials

   Preparation: Going through course materials

2. WEEK 2

   Mechanical and Surface Properties of Biomaterials

   Preparation: Going through course materials

3. WEEK 3

   Polymeric Biomaterials

   Preparation: Going through course materials

4. WEEK 4

   Polymeric Biomaterials, Dental Biomaterials and Hydrogels

   Preparation: Going through course materials

5. WEEK 5

   Degradation of Biomaterials

   Preparation: Going through course materials

6. WEEK 6

   Metalic Biomaterials

   Preparation: Going through course materials

7. WEEK 7

   Ceramic Biomaterials

   Preparation: Going through course materials

8. WEEK 8

   Composite Biomaterials

   Preparation: Going through course materials

9. WEEK 9

   Macro and Nanoparticles

   Preparation: Going through course materials

10. WEEK 10

    Processing of Biomaterials

    Preparation: Going through course materials

11. WEEK 11

    Biomaterials-Protein Interaction

    Preparation: Going through course materials

12. WEEK 12

    Host Response to Biomaterials

    Preparation: Going through course materials

13. WEEK 13

    Testing Biomaterials

    Preparation: Going through course materials

14. WEEK 14

    Production and Life Cycle of Biomaterials and Commercialization Paths

    Preparation: Going through course materials

ASSESSMENT

• Rate of Midterm Exam to Success30%
• Rate of Final Exam to Success70%

WORKLOAD

READING

• Biomaterials, The intersection of Biology and Materials Science- J.S. Temenoff, A.G. Mikos, lecture notes and presentations
• 1. Biomaterials Science, An introduction to Materials in Medicine- B.D. Ratner, A.S. Hoffman, F.J. Schoen, J.E. Lemons 2. “Biomaterials Science: An Introduction to Materials in Medicine”, B.D. Ratner, A.S. Hoffman, F.J. Schoen, J.E. Lemans, Academic Press, 1996

TEACHING STAFF

• Prof.Dr. Yasemin YÜKSEL DURMAZCOORDINATOR
• Prof.Dr. Yasemin YÜKSEL DURMAZ
• Assist.Prof. Mehmet Hikmet ÜÇIŞIK