CELLULAR and MOLECULAR BIOLOGY

AIM

It is aimed to convey molecular-level knowledge pertaining to mechanism of cellular processes to 2 nd year biomedical engineering students in this course. Moreover, any types of experiment related to biology in the field of biomedical engineering will also be practiced.

CONTENT

This course contains; Proteins, DNA and chromosomes ,DNA replication, repair and recombination ,Protein Synthesis ,DNA isolation, cloning, and DNA sequencing-I,DNA isolation, cloning, and DNA sequencing -II,Polimerase Chain Reaction, Chromatographic Methods,Construction of Genomic and C-DNA Libraries,SDS-Gel Electrophoresis, Yeast two hybridization method,Cell Cycle and Programmed Cell Death -I,Cell Cycle, Programmed Cell Death-II,Cancer-I,Cancer-II,Presentations-I,Presentations-II.

1. 1

   1) Analyze the basic concepts regarding molecular and cellular biology on a comparative basis.

   Taught by: Discussion Method, Self Study Method, Question - Answer Technique, Experimental Technique, Brainstorming Technique, Reverse Brainstorming Technique, Computer-Internet Supported Instruction, Cooperative Learning · Assessed by: Traditional Written Exam, Project Task, Quiz

2. 2

   2) Capable of testing concepts related to cellular biology by means of experiments.

   Taught by: Discussion Method, Problem Solving Method, Case Study Method, Self Study Method, Question - Answer Technique, Experimental Technique, Reverse Brainstorming Technique, Cooperative Learning · Assessed by: Quiz

3. 3

   3) Capable of analyzing some cellular biology related hot topics

   Taught by: Discussion Method, Problem Solving Method, Case Study Method, Brainstorming Technique, Reverse Brainstorming Technique, Simulation Technique

4. 4

   4) Capable of analyzing, organizing, discussing results of experiments and expressing them by his/her own.

   Taught by: Discussion Method, Self Study Method, Experimental Technique, Brainstorming Technique, Reverse Brainstorming Technique, Lecture Method · Assessed by: Project Task, Quiz

5. 5

   5)Combining different concepts regarding cell division, the onset of cancer can be studied on a cause-effect basis.

   Taught by: Discussion Method, Problem Solving Method, Self Study Method, Problem Baded Learning Model, Inquiry-Based Learning

WEEKLY PLAN

1. WEEK 1

   Proteins, DNA and chromosomes

2. WEEK 2

   DNA replication, repair and recombination

3. WEEK 3

   Protein Synthesis

4. WEEK 4

   DNA isolation, cloning, and DNA sequencing-I

5. WEEK 5

   DNA isolation, cloning, and DNA sequencing -II

6. WEEK 6

   Polimerase Chain Reaction, Chromatographic Methods

7. WEEK 7

   Construction of Genomic and C-DNA Libraries

8. WEEK 8

   SDS-Gel Electrophoresis, Yeast two hybridization method

9. WEEK 9

   Cell Cycle and Programmed Cell Death -I

10. WEEK 10

    Cell Cycle, Programmed Cell Death-II

11. WEEK 11

    Cancer-I

12. WEEK 12

    Cancer-II

13. WEEK 13

    Presentations-I

14. WEEK 14

    Presentations-II

ASSESSMENT

• Rate of Midterm Exam to Success30%
• Rate of Final Exam to Success70%

WORKLOAD

READING

• Molecular Biology of the Cell, 5 th Edition, Alberts, Johnson, Lewis, Raff, Roberts, Walter Sunum, hands-on
• 1) Molecular Biology of the Cell, 5 th Edition, Alberts, Johnson, Lewis, Raff, Roberts, Walter 2) Essential Cell Biology, 3 rd Edition, Alberts, Bray, Hopkin, Johnson, Johnson, Lewis, Raff, Roberts

TEACHING STAFF

• Assoc.Prof. Özge ŞENSOYCOORDINATOR
• Assoc.Prof. Özge ŞENSOY
• Res.Assist. SEMİH MACİT
• Res.Assist. Birgün ÖZÇOLAK ASLAN