BIOSENSORS

AIM

Underlying engineering principles used to detect small molecules, DNA, proteins, and cells in the context of applications in diagnostic testing, pharmaceutical research, and environmental monitoring. Biosensor approaches including electrochemistry, fluorescence, acoustics, and optics; aspects of selective surface chemistry including methods for biomolecule attachment to transducer surfaces; characterization of bisensor performance; blood glucose detection; fluorescent DNA microarrays; label-free biochips; bead-based assay methods. Case studies and analysis of commercial biosensor.

CONTENT

This course contains; Introduction to Biosensors,Biological elements,Immobilization of biological elements,Electrochemical transducers,Optical transducers,Piezoelectric transducers,Immunosensors,Figures of merit,Lab-on-a-chip biosensors,Nanobiosensors,Applications of biosensors,Application of Biosensors-II,Bendable and stretchable bioelectronics-I,Bendable and stretchable bioelectronics-II.

1. 1

   Defines the fundamental concepts behind the operation of the most important classes of biosensors

   Taught by: Case Study Method, Experimental Technique, Brainstorming Technique, Lecture Method · Assessed by: Traditional Written Exam, Homework

2. 2

   Recognize how biosensors are characterized, compared to each other, and designed to suit particular applications

   Taught by: Case Study Method, Experimental Technique, Brainstorming Technique, Lecture Method · Assessed by: Traditional Written Exam, Homework

3. 3

   Evaluates how biochemical functionality is coupled to a biosensor transducer

   Taught by: Case Study Method, Experimental Technique, Brainstorming Technique, Lecture Method · Assessed by: Traditional Written Exam, Homework

4. 4

   Recognizes the major applications of biosensor technology in diagnostic tests, life science research, and environmental testing

   Taught by: Case Study Method, Experimental Technique, Brainstorming Technique, Lecture Method · Assessed by: Traditional Written Exam, Homework

5. 5

   Rocognizes several of the most important emerging biosensor technologies

   Taught by: Case Study Method, Experimental Technique, Brainstorming Technique, Lecture Method · Assessed by: Traditional Written Exam

6. 6

   Gains the practice of critical thinking when considering a new detection technology and to develop the ability to communicate well-researched opinions to others

   Taught by: Case Study Method, Experimental Technique, Brainstorming Technique, Lecture Method · Assessed by: Traditional Written Exam

WEEKLY PLAN

1. WEEK 1

   Introduction to Biosensors

   Preparation: Going through course materials

2. WEEK 2

   Biological elements

   Preparation: Going through course materials

3. WEEK 3

   Immobilization of biological elements

   Preparation: Going through course materials

4. WEEK 4

   Electrochemical transducers

   Preparation: Going through course materials

5. WEEK 5

   Optical transducers

   Preparation: Going through course materials

6. WEEK 6

   Piezoelectric transducers

   Preparation: Going through course materials

7. WEEK 7

   Immunosensors

   Preparation: Going through course materials

8. WEEK 8

   Figures of merit

   Preparation: Going through course materials

9. WEEK 9

   Lab-on-a-chip biosensors

   Preparation: Going through course materials

10. WEEK 10

    Nanobiosensors

    Preparation: Going through course materials

11. WEEK 11

    Applications of biosensors

    Preparation: Going through course materials

12. WEEK 12

    Application of Biosensors-II

    Preparation: Going through course materials

13. WEEK 13

    Bendable and stretchable bioelectronics-I

    Preparation: Going through course materials

14. WEEK 14

    Bendable and stretchable bioelectronics-II

    Preparation: Going through course materials

ASSESSMENT

• Rate of Midterm Exam to Success30%
• Rate of Final Exam to Success70%

WORKLOAD

READING

• Gennady Evtugyn, "Biosensors: Essentials", Springer, 2014
• Jeong-Yeol Yoon, "Introduction to Biosensors", Springer, 2016

TEACHING STAFF

• Assoc.Prof. Hasan KURTCOORDINATOR
• Assoc.Prof. Hasan KURT