BIOMEDICAL OPTICS

AIM

The aim of this course is to develop novel solutions to problems in the fields of biology and medical sciences utilizing optical methods and to evaluate existing solutions.

CONTENT

This course contains; Overview of basic principles in optics,Light sources and detectors,Linear and nonlinear spectroscopy,Light propagation in turbid media,Interaction of light with cells and tissues,Optical microscopy methods,Optical coherence tomography,Diffuse optical tomography,Photoacoustic tomography,Optical biosensors,Microarray technology for genomics and proteomics, Flow cytometry,Laser tweezers,Photodynamic therapy.

1. 1

   Apply optical concepts to monitor biomedical parameters

   Taught by: Experiential Learning, Lecture Method · Assessed by: Traditional Written Exam, Project Task

2. 2

   Analyze the light propagation in turbid media

   Taught by: Project Based Learning Model, Lecture Method · Assessed by: Traditional Written Exam, Project Task

3. 3

   Explain various biomedical optical techniques and systems

   Taught by: Project Based Learning Model, Experiential Learning, Lecture Method · Assessed by: Traditional Written Exam, Project Task

4. 4

   Design application specific microscopy systems

   Taught by: Experiential Learning, Lecture Method · Assessed by: Traditional Written Exam, Project Task

5. 5

   Evaluate the performance of various optical methods for biomedical applications

   Taught by: Experiential Learning, Lecture Method · Assessed by: Traditional Written Exam, Project Task

WEEKLY PLAN

1. WEEK 1

   Overview of basic principles in optics

2. WEEK 2

   Light sources and detectors

3. WEEK 3

   Linear and nonlinear spectroscopy

4. WEEK 4

   Light propagation in turbid media

5. WEEK 5

   Interaction of light with cells and tissues

6. WEEK 6

   Optical microscopy methods

7. WEEK 7

   Optical coherence tomography

8. WEEK 8

   Diffuse optical tomography

9. WEEK 9

   Photoacoustic tomography

10. WEEK 10

    Optical biosensors

11. WEEK 11

    Microarray technology for genomics and proteomics

12. WEEK 12

    Flow cytometry

13. WEEK 13

    Laser tweezers

14. WEEK 14

    Photodynamic therapy

ASSESSMENT

• Rate of Midterm Exam to Success30%
• Rate of Final Exam to Success70%

WORKLOAD

READING

• Introduction to Biophotonics, by Paras N. Prasad (John Wiley & Sons, Inc., 2003).Biomedical Optics: Principles and Imaging by Lihong V. Wang and Hsin-i Wu, (John Wiley & Sons, Inc., 2007).

TEACHING STAFF

• Assoc.Prof. Muhammed Fatih TOYCOORDINATOR
• Assoc.Prof. Muhammed Fatih TOY