ADVANCED BIOMEDICAL OPTICS

AIM

The aim of this course is to develop novel solutions to problems in the fields of biology and medical sciences utilizing optical methods and to evaluate existing solutions.

CONTENT

This course contains; 1. Overview of basic principles in optics,2. Light sources and detectors,3. Linear and nonlinear spectroscopy,4. Light propagation in turbid media,5. Interaction of light with cells and tissues,6. Optical microscopy methods,7. Optical coherence tomography,8. Diffuse optical tomography,9. Photoacoustic tomography,10. Optical biosensors,11. Microarray technology for genomics and proteomics,12. Flow cytometry,13. Laser tweezers,14. Photodynamic therapy.

1. 1

   1. Apply optical concepts to monitor biomedical parameters

   Taught by: Experiential Learning, Lecture Method · Assessed by: Traditional Written Exam, Project Task

2. 2

   2. Analyze the light propagation in turbid media

   Taught by: Discussion Method, Brainstorming Technique, Lecture Method · Assessed by: Traditional Written Exam

3. 3

   3. Understand and explain various biomedical optical techniques and systems

   Taught by: Discussion Method, Brainstorming Technique, Experiential Learning, Lecture Method · Assessed by: Traditional Written Exam, Project Task

4. 4

   4. Design application specific microscopy systems

   Taught by: Experiential Learning, Lecture Method · Assessed by: Traditional Written Exam, Project Task

5. 5

   5. Evaluate the performance of various optical methods for biomedical applications

   Taught by: Experiential Learning, Lecture Method · Assessed by: Traditional Written Exam, Project Task

WEEKLY PLAN

1. WEEK 1

   1. Overview of basic principles in optics

2. WEEK 2

   2. Light sources and detectors

3. WEEK 3

   3. Linear and nonlinear spectroscopy

4. WEEK 4

   4. Light propagation in turbid media

5. WEEK 5

   5. Interaction of light with cells and tissues

6. WEEK 6

   6. Optical microscopy methods

7. WEEK 7

   7. Optical coherence tomography

8. WEEK 8

   8. Diffuse optical tomography

9. WEEK 9

   9. Photoacoustic tomography

10. WEEK 10

    10. Optical biosensors

11. WEEK 11

    11. Microarray technology for genomics and proteomics

12. WEEK 12

    12. Flow cytometry

13. WEEK 13

    13. Laser tweezers

14. WEEK 14

    14. Photodynamic therapy

ASSESSMENT

• Rate of Midterm Exam to Success50%
• Rate of Final Exam to Success50%

WORKLOAD

READING

• Introduction to Biophotonics, by Paras N. Prasad (John Wiley & Sons, Inc., 2003).
• Biomedical Optics: Principles and Imaging by Lihong V. Wang and Hsin-i Wu, (John Wiley & Sons, Inc., 2007).

TEACHING STAFF

• Assoc.Prof. Muhammed Fatih TOYCOORDINATOR
• Assoc.Prof. Muhammed Fatih TOY